International Knockout Mouse Consortium - Knowledgebase

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folder Screens and Quality Control (3)


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document How can I determine the knockout status of my gene?
Enter the gene symbol into the search box on the upper right and search. The resulting query summary lists one record (row) for each gene that matches your query.
19 September 2011
document How is the "critical" exon decided in CSD alleles?
A number of criteria are applied when choosing the critical exon for a KOMP-CSD or EUCOMM allele, but not every gene can have all criteria fulfilled:
27 April 2011
document What are the IKMC allele types?
Summary of all IKMC allele types The wild-type is represented as a transcript with three exons. The ‘floxed’ exon (the exon that will be deleted for the null allele) is exon number 2.
24 August 2010
document Which Exons Are "Floxed" by My Conditional Knockout?
You can find this out yourself by following these steps:
05 August 2010
document What genes are in the IKMC database?
The IKMC database includes all genes from the Mouse Genome Informatics (MGI) database for which sequences and genome coordinates are available. This includes all genes predicted by the NCBI, Ensembl, and Vega (Vertebrate Genome Annotation) pipelin...
27 January 2010
document What products are being generated by IKMC?
The main emphasis of IKMC (as currently funded) is to generate targeting vectors and mutant ES cells. Only for a limited number of genes, mutant mice, embryos or sperm will be generated by the production centers. However, for KOMP, the KOMP Reposi...
15 December 2009
document My gene is in the production pipeline. How long will it take until vectors, mutant ES cells, mutant mice are available?
The IKMC Project has been complete and no more Targeting Vectors or ES Cells will be constructed by the IKMC.
15 December 2009
document How can I order IKMC products?
To order IKMC products you can search the IKMC database and follow the order links on the gene status details page (see above).
15 December 2009
document Can I receive email notification when IKMC products for my gene are available?
Yes. To see what products are available go to the IMPC website and search for your gene of interest using the Product Search box.
15 December 2009
document Can I nominate genes for targeting by IKMC/IMPC? Can I raise the priority for genes that are on the IKMC/IMPC gene list?
The answer to both questions is yes. IMPC welcomes gene nomination and prioritization requests from the research community. Please register interest in a gene on the IMPC website to nomination a gene. All submissions will be forwarded to and consi...
15 December 2009
document How can I browse the IKMC database?
The IKMC database has moved and is now available through the IMPC portal.
15 December 2009

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